|Occupation||Deputy SEP Account Manager|
|Voice|| Candi Milo|
Cree Summer (Op. T.O.M.M.Y.)
|Cameos|| Operation: L.O.V.E.|
Operation: T.R.I.K.E. (comic)
She is perhaps more aware of the KND's presence than any other operative's parents (Except, of course, for Mr. Boss, father of Numbuh 86). She used some hi-tech gadgetry of her own to stop the Common Cold (Operation: T.O.M.M.Y.), and is aware of her son's use of 2x4 technology, most notably a security system he installed in the house, as seen in Operation: C.L.U.E.S.. She tried to impress Kuki's mother - her boss - in this episode, and succeeded thanks to Numbuh 2.
- Betty Gilligan was voiced by Cree Summer in her first appearance, Operation: T.O.M.M.Y..
- Betty Gilligan's knowledge of Numbuh 2's 2x4 technology and the KND itself could indicate that she is an ally of Sector V.
- This may also imply that she was once a KND operative herself, and she somehow remembers her knowledge after being decommissioned.
- It is unknown where her husband is. He could either be divorced or deceased, or simply absent in the show.
- In the comic Operation: T.R.I.K.E., she is seen with blonde hair.
- She speaks with a Minnesotan accent.